Highlights of previous work

Alison Vander Roest*, Chao Liu*, Makenna Morck, Kristi Kooiker, Gina Jung, Dan Song, Aminah Dawood, Gaspard Pardon, Arnav Jhingran, Sara Vaziri, Giovanni Fajardo, Mingming Zhao, Kenneth Campbell, Beth Pruitt, James Spudich, Kathleen Ruppel, Daniel Bernstein. Hypertrophic cardiomyopathy β-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super relaxed state, PNAS 2021 118 (24) e2025030118

Graphs describing representative cells and traction forces
Graphs describing representative cells and traction forces

Review: Alison Schroer, Gaspard Pardon, Erica Castillo, Cheavar Blair, Beth Pruitt. Engineering hiPSC cardiomyocyte in vitro model systems for functional and structural assessment, Prog. Biophys Mol Biol. 2018 144:3-15

Diagram of native cardiac environment

Alison Schroer, Matthew Bersi, Cynthia Clark, Q Zhang, Lehanna Sanders, Antonis Hatzopoulos, Thomas Force, Susan Majka, Hind Lal, W David Merryman. Cadherin-11 blockade reduces inflammation-driven fibrotic remodeling and improves outcomes after myocardial infarction, JCI Insight, 2019 4(18).

Graphics describing post-myocardial infarction results
Graphs describing ejection fraction, LV mass, and LV volume in days post-myocardial infarction

Review: Alison Schroer, David Merryman Mechanobiology of myofibroblast adhesion in fibrotic cardiac disease, JCS, 2015 Vol. 128(10):1865-75.

Diagram of a heart

Full list of publications